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Expression of interferon-induced antiviral genes is delayed in a STAT1 knockout mouse model of Crimean-Congo hemorrhagic fever

BACKGROUND: Crimean Congo hemorrhagic fever (CCHF) is a tick-borne hemorrhagic zoonosis associated with high mortality. Pathogenesis studies and the development of vaccines and antivirals against CCHF have been severely hampered by the lack of suitable animal model. We recently developed and charact...

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Detalles Bibliográficos
Autores principales: Bowick, Gavin C, Airo, Adriana M, Bente, Dennis A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489622/
https://www.ncbi.nlm.nih.gov/pubmed/22713837
http://dx.doi.org/10.1186/1743-422X-9-122