Effects on human transcriptome of mutated BRCA1 BRCT domain: A microarray study

BACKGROUND: BRCA1 (breast cancer 1, early onset) missense mutations have been detected in familial breast and ovarian cancers, but the role of these variants in cancer predisposition is often difficult to ascertain. In this work, the molecular mechanisms affected in human cells by two BRCA1 missense...

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Detalles Bibliográficos
Autores principales: Iofrida, Caterina, Melissari, Erika, Mariotti, Veronica, Guglielmi, Chiara, Guidugli, Lucia, Caligo, Maria Adelaide, Pellegrini, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489683/
https://www.ncbi.nlm.nih.gov/pubmed/22646717
http://dx.doi.org/10.1186/1471-2407-12-207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489683/
https://www.ncbi.nlm.nih.gov/pubmed/22646717
http://dx.doi.org/10.1186/1471-2407-12-207

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