Treatment with a Nitric Oxide-Donating NSAID Alleviates Functional Muscle Ischemia in the Mouse Model of Duchenne Muscular Dystrophy

In patients with Duchenne muscular dystrophy (DMD) and the standard mdx mouse model of DMD, dystrophin deficiency causes loss of neuronal nitric oxide synthase (nNOSμ) from the sarcolemma, producing functional ischemia when the muscles are exercised. We asked if functional muscle ischemia would be e...

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Detalles Bibliográficos
Autores principales: Thomas, Gail D., Ye, Jianfeng, De Nardi, Claudio, Monopoli, Angela, Ongini, Ennio, Victor, Ronald G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489726/
https://www.ncbi.nlm.nih.gov/pubmed/23139842
http://dx.doi.org/10.1371/journal.pone.0049350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489726/
https://www.ncbi.nlm.nih.gov/pubmed/23139842
http://dx.doi.org/10.1371/journal.pone.0049350

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