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High endothelial venules (HEVs) in human melanoma lesions: Major gateways for tumor-infiltrating lymphocytes
The presence of tumor-infiltrating lymphocytes (TILs) is a strong prognostic parameter for local dissemination and overall survival in melanoma. Lymphocyte migration from blood into peripheral tissues is mainly regulated by vascular endothelium. However, the blood vessels and mechanisms governing th...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489738/ https://www.ncbi.nlm.nih.gov/pubmed/23162750 http://dx.doi.org/10.4161/onci.20492 |