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Viral antigen mediated NKp46 activation of NK cells results in tumor rejection via NK-DC crosstalk

Natural killer (NK) cells play a critical role in antitumor immunity, their activation being regulated through NK cell receptors. Although the endogenous ligands for these receptors are largely unknown, viral ligands have been identified. We investigated the ability of an activating NK receptor liga...

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Detalles Bibliográficos
Autores principales: Chinnery, Fay, King, Catherine A., Elliott, Tim, Bateman, Andrew R., James, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489743/
https://www.ncbi.nlm.nih.gov/pubmed/23162755
http://dx.doi.org/10.4161/onci.20636