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"Flagellated" cancer cells propel anti-tumor immunity

The use of innate immune receptor agonists in cancer therapies has suffered from many drawbacks. Our recent observations suggest that some of these hurdles can be overcome by introducing flagellin into tumor cells to promote tumor antigen presentation by dendritic cells (DCs) and simultaneously trig...

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Detalles Bibliográficos
Autores principales: Garaude, Johan, Blander, J. Magarian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489752/
https://www.ncbi.nlm.nih.gov/pubmed/23162764
http://dx.doi.org/10.4161/onci.20305