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How two sites of inflammation promote carcinogenesis: The role of macrophages in inflammation associated carcinogenesis

We recently reported that anti-inflammatory macrophages contribute to the initiation of colorectal carcinogenesis in IBD patients by inducing epithelial-mesenchymal-transition associated alterations in colonic epithelial cells. In this process, TGFβ1 dependent upregulation of the adhesion molecule L...

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Detalles Bibliográficos
Autores principales: Sebens, Susanne, Schäfer, Heiner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489756/
https://www.ncbi.nlm.nih.gov/pubmed/23162768
http://dx.doi.org/10.4161/onci.19949