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Within tumors, interactions between T cells and tumor cells are impeded by the extracellular matrix

In principle, T cells can recognize and kill cancer cells. However, tumors have the ability to escape T cell attack. By imaging the dynamic behavior of T cells in human lung tumor explants, we have recently established the importance of the extracellular matrix in limiting access of T cells to tumor...

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Detalles Bibliográficos
Autores principales: Salmon, Hélène, Donnadieu, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489771/
https://www.ncbi.nlm.nih.gov/pubmed/23162783
http://dx.doi.org/10.4161/onci.20239