Within tumors, interactions between T cells and tumor cells are impeded by the extracellular matrix

In principle, T cells can recognize and kill cancer cells. However, tumors have the ability to escape T cell attack. By imaging the dynamic behavior of T cells in human lung tumor explants, we have recently established the importance of the extracellular matrix in limiting access of T cells to tumor...

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Detalles Bibliográficos
Autores principales: Salmon, Hélène, Donnadieu, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489771/
https://www.ncbi.nlm.nih.gov/pubmed/23162783
http://dx.doi.org/10.4161/onci.20239
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author Salmon, Hélène
Donnadieu, Emmanuel
author_facet Salmon, Hélène
Donnadieu, Emmanuel
author_sort Salmon, Hélène
collection PubMed
description In principle, T cells can recognize and kill cancer cells. However, tumors have the ability to escape T cell attack. By imaging the dynamic behavior of T cells in human lung tumor explants, we have recently established the importance of the extracellular matrix in limiting access of T cells to tumor cells.
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spelling pubmed-34897712012-11-16 Within tumors, interactions between T cells and tumor cells are impeded by the extracellular matrix Salmon, Hélène Donnadieu, Emmanuel Oncoimmunology Author's View In principle, T cells can recognize and kill cancer cells. However, tumors have the ability to escape T cell attack. By imaging the dynamic behavior of T cells in human lung tumor explants, we have recently established the importance of the extracellular matrix in limiting access of T cells to tumor cells. Landes Bioscience 2012-09-01 /pmc/articles/PMC3489771/ /pubmed/23162783 http://dx.doi.org/10.4161/onci.20239 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Salmon, Hélène
Donnadieu, Emmanuel
Within tumors, interactions between T cells and tumor cells are impeded by the extracellular matrix
title Within tumors, interactions between T cells and tumor cells are impeded by the extracellular matrix
title_full Within tumors, interactions between T cells and tumor cells are impeded by the extracellular matrix
title_fullStr Within tumors, interactions between T cells and tumor cells are impeded by the extracellular matrix
title_full_unstemmed Within tumors, interactions between T cells and tumor cells are impeded by the extracellular matrix
title_short Within tumors, interactions between T cells and tumor cells are impeded by the extracellular matrix
title_sort within tumors, interactions between t cells and tumor cells are impeded by the extracellular matrix
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489771/
https://www.ncbi.nlm.nih.gov/pubmed/23162783
http://dx.doi.org/10.4161/onci.20239
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