Airway protease/antiprotease imbalance in atopic asthmatics contributes to increased Influenza A virus cleavage and replication

Asthmatics are more susceptible to influenza infections, yet mechanisms mediating this enhanced susceptibility are unknown. Influenza virus hemagglutinin (HA) protein binds to sialic acid residues on the host cells. HA requires cleavage to allow fusion of the viral HA with host cell membrane, which...

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Detalles Bibliográficos
Autores principales: Kesic, Matthew J, Hernandez, Michelle, Jaspers, Ilona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489803/
https://www.ncbi.nlm.nih.gov/pubmed/22992220
http://dx.doi.org/10.1186/1465-9921-13-82

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489803/
https://www.ncbi.nlm.nih.gov/pubmed/22992220
http://dx.doi.org/10.1186/1465-9921-13-82

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