Role of C-terminal negative charges and tyrosine residues in fibril formation of α-synuclein

α-Synuclein (140 amino acids), one of the causative proteins of Parkinson's disease, forms amyloid fibrils in brain neuronal cells. In order to further explore the contributions of the C-terminal region of α-synuclein in fibril formation and also to understand the overall mechanism of fibril fo...

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Detalles Bibliográficos
Autores principales: Izawa, Yasutaka, Tateno, Hironobu, Kameda, Hiroshi, Hirakawa, Kazuya, Hato, Keiko, Yagi, Hisashi, Hongo, Kunihiro, Mizobata, Tomohiro, Kawata, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Inc 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489812/
https://www.ncbi.nlm.nih.gov/pubmed/23139905
http://dx.doi.org/10.1002/brb3.86

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489812/
https://www.ncbi.nlm.nih.gov/pubmed/23139905
http://dx.doi.org/10.1002/brb3.86

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