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The A736V TMPRSS6 Polymorphism Influences Hepatic Iron Overload in Nonalcoholic Fatty Liver Disease

BACKGROUND & AIMS: Hepatic iron accumulation due to altered trafficking is frequent in patients with nonalcoholic fatty liver disease (NAFLD), and is associated with more severe liver damage and hepatocellular carcinoma. The p.Ala736Val TMPRSS6 variant influences iron metabolism regulating the t...

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Detalles Bibliográficos
Autores principales: Valenti, Luca, Rametta, Raffaela, Dongiovanni, Paola, Motta, Benedetta M., Canavesi, Elena, Pelusi, Serena, Pulixi, Edoardo A., Fracanzani, Anna L., Fargion, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489825/
https://www.ncbi.nlm.nih.gov/pubmed/23144979
http://dx.doi.org/10.1371/journal.pone.0048804