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The A736V TMPRSS6 Polymorphism Influences Hepatic Iron Overload in Nonalcoholic Fatty Liver Disease
BACKGROUND & AIMS: Hepatic iron accumulation due to altered trafficking is frequent in patients with nonalcoholic fatty liver disease (NAFLD), and is associated with more severe liver damage and hepatocellular carcinoma. The p.Ala736Val TMPRSS6 variant influences iron metabolism regulating the t...
Autores principales: | Valenti, Luca, Rametta, Raffaela, Dongiovanni, Paola, Motta, Benedetta M., Canavesi, Elena, Pelusi, Serena, Pulixi, Edoardo A., Fracanzani, Anna L., Fargion, Silvia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489825/ https://www.ncbi.nlm.nih.gov/pubmed/23144979 http://dx.doi.org/10.1371/journal.pone.0048804 |
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