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The role of versican G3 domain in regulating breast cancer cell motility including effects on osteoblast cell growth and differentiation in vitro – evaluation towards understanding breast cancer cell bone metastasis

BACKGROUND: Versican is detected in the interstitial tissues at the invasive margins of breast carcinoma, is predictive of relapse, and negatively impacts overall survival rates. The versican G3 domain is important in breast cancer cell growth, migration and bone metastasis. However, mechanistic stu...

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Detalles Bibliográficos
Autores principales: Du, William Weidong, Fang, Ling, Yang, Weining, Sheng, Wang, Zhang, Yaou, Seth, Arun, Yang, Burton B, Yee, Albert J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489894/
https://www.ncbi.nlm.nih.gov/pubmed/22862967
http://dx.doi.org/10.1186/1471-2407-12-341