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Allele-Level Haplotype Frequencies and Pairwise Linkage Disequilibrium for 14 KIR Loci in 506 European-American Individuals

The immune responses of natural killer cells are regulated, in part, by killer cell immunoglobulin-like receptors (KIR). The 16 closely-related genes in the KIR gene system have been diversified by gene duplication and unequal crossing over, thereby generating haplotypes with variation in gene copy...

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Detalles Bibliográficos
Autores principales: Vierra-Green, Cynthia, Roe, David, Hou, Lihua, Hurley, Carolyn Katovich, Rajalingam, Raja, Reed, Elaine, Lebedeva, Tatiana, Yu, Neng, Stewart, Mary, Noreen, Harriet, Hollenbach, Jill A., Guethlein, Lisbeth A., Wang, Tao, Spellman, Stephen, Maiers, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489906/
https://www.ncbi.nlm.nih.gov/pubmed/23139747
http://dx.doi.org/10.1371/journal.pone.0047491