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Neo-Islet Formation in Liver of Diabetic Mice by Helper-dependent Adenoviral Vector-Mediated Gene Transfer

Type 1 diabetes is caused by T cell-mediated autoimmune destruction of insulin-producing cells in the pancreas. Until now insulin replacement is still the major therapy, because islet transplantation has been limited by donor availability and by the need for long-term immunosuppression. Induced isle...

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Detalles Bibliográficos
Autores principales: Li, Rongying, Oka, Kazuhiro, Yechoor, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490299/
https://www.ncbi.nlm.nih.gov/pubmed/23093064
http://dx.doi.org/10.3791/4321