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Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE Collaboration): a meta-analysis of genome-wide association studies

BACKGROUND: Various genome-wide association studies (GWAS) have been done in ischaemic stroke, identifying a few loci associated with the disease, but sample sizes have been 3500 cases or less. We established the METASTROKE collaboration with the aim of validating associations from previous GWAS and...

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Detalles Bibliográficos
Autores principales: Traylor, Matthew, Farrall, Martin, Holliday, Elizabeth G, Sudlow, Cathie, Hopewell, Jemma C, Cheng, Yu-Ching, Fornage, Myriam, Ikram, M Arfan, Malik, Rainer, Bevan, Steve, Thorsteinsdottir, Unnur, Nalls, Mike A, Longstreth, WT, Wiggins, Kerri L, Yadav, Sunaina, Parati, Eugenio A, DeStefano, Anita L, Worrall, Bradford B, Kittner, Steven J, Khan, Muhammad Saleem, Reiner, Alex P, Helgadottir, Anna, Achterberg, Sefanja, Fernandez-Cadenas, Israel, Abboud, Sherine, Schmidt, Reinhold, Walters, Matthew, Chen, Wei-Min, Ringelstein, E Bernd, O'Donnell, Martin, Ho, Weang Kee, Pera, Joanna, Lemmens, Robin, Norrving, Bo, Higgins, Peter, Benn, Marianne, Sale, Michele, Kuhlenbäumer, Gregor, Doney, Alexander S F, Vicente, Astrid M, Delavaran, Hossein, Algra, Ale, Davies, Gail, Oliveira, Sofia A, Palmer, Colin N A, Deary, Ian, Schmidt, Helena, Pandolfo, Massimo, Montaner, Joan, Carty, Cara, de Bakker, Paul I W, Kostulas, Konstantinos, Ferro, Jose M, van Zuydam, Natalie R, Valdimarsson, Einar, Nordestgaard, Børge G, Lindgren, Arne, Thijs, Vincent, Slowik, Agnieszka, Saleheen, Danish, Paré, Guillaume, Berger, Klaus, Thorleifsson, Gudmar, Hofman, Albert, Mosley, Thomas H, Mitchell, Braxton D, Furie, Karen, Clarke, Robert, Levi, Christopher, Seshadri, Sudha, Gschwendtner, Andreas, Boncoraglio, Giorgio B, Sharma, Pankaj, Bis, Joshua C, Gretarsdottir, Solveig, Psaty, Bruce M, Rothwell, Peter M, Rosand, Jonathan, Meschia, James F, Stefansson, Kari, Dichgans, Martin, Markus, Hugh S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lancet Pub. Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490334/
https://www.ncbi.nlm.nih.gov/pubmed/23041239
http://dx.doi.org/10.1016/S1474-4422(12)70234-X