Acceleration of Gastric Tumorigenesis Through MKRN1-Mediated Posttranslational Regulation of p14ARF

BACKGROUND: We investigated whether Makorin ring finger protein 1 (MKRN1), an E3 ligase, affects p14ARF-associated cellular senescence and tumorigenesis by posttranslational modification in gastric tumorigenesis. METHODS: A link between MKRN1 and ARF was examined in MKRN1 null mouse embryonic fibrob...

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Detalles Bibliográficos
Autores principales: Ko, Aram, Shin, Ji-Young, Seo, Jinho, Lee, Kang-Duck, Lee, Eun-Woo, Lee, Min-Sik, Lee, Han-Woong, Choi, Il-Ju, Jeong, Jin Sook, Chun, Kyung-Hee, Song, Jaewhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490844/
https://www.ncbi.nlm.nih.gov/pubmed/23104211
http://dx.doi.org/10.1093/jnci/djs424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490844/
https://www.ncbi.nlm.nih.gov/pubmed/23104211
http://dx.doi.org/10.1093/jnci/djs424

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