Random Phenotypic Variation of Yeast (Saccharomyces cerevisiae) Single-Gene Knockouts Fits a Double Pareto-Lognormal Distribution

BACKGROUND: Distributed robustness is thought to influence the buffering of random phenotypic variation through the scale-free topology of gene regulatory, metabolic, and protein-protein interaction networks. If this hypothesis is true, then the phenotypic response to the perturbation of particular...

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Detalles Bibliográficos
Autores principales: Graham, John H., Robb, Daniel T., Poe, Amy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490920/
https://www.ncbi.nlm.nih.gov/pubmed/23139826
http://dx.doi.org/10.1371/journal.pone.0048964

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490920/
https://www.ncbi.nlm.nih.gov/pubmed/23139826
http://dx.doi.org/10.1371/journal.pone.0048964

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