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Distinct Cellular and Subcellular Distributions of G Protein-Coupled Receptor Kinase and Arrestin Isoforms in the Striatum

G protein-coupled receptor kinases (GRKs) and arrestins mediate desensitization of G protein-coupled receptors (GPCR). Arrestins also mediate G protein-independent signaling via GPCRs. Since GRK and arrestins demonstrate no strict receptor specificity, their functions in the brain may depend on thei...

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Detalles Bibliográficos
Autores principales: Bychkov, Evgeny, Zurkovsky, Lilia, Garret, Mika B., Ahmed, Mohamed R., Gurevich, Eugenia V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490921/
https://www.ncbi.nlm.nih.gov/pubmed/23139825
http://dx.doi.org/10.1371/journal.pone.0048912