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Polymorphisms in the genes coding for iron binding and transporting proteins are associated with disability, severity, and early progression in multiple sclerosis

BACKGROUND: Iron involvement/imbalance is strongly suspected in multiple sclerosis (MS) etiopathogenesis, but its role is quite debated. Iron deposits encircle the veins in brain MS lesions, increasing local metal concentrations in brain parenchyma as documented by magnetic resonance imaging and his...

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Detalles Bibliográficos
Autores principales: Gemmati, Donato, Zeri, Giulia, Orioli, Elisa, De Gaetano, Francesca E, Salvi, Fabrizio, Bartolomei, Ilaria, D’Alfonso, Sandra, Dall’Osso, Claudia, Leone, Maurizio A, Singh, Ajay V, Asselta, Rosanna, Zamboni, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490944/
https://www.ncbi.nlm.nih.gov/pubmed/22883388
http://dx.doi.org/10.1186/1471-2350-13-70