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Polymorphisms in the genes coding for iron binding and transporting proteins are associated with disability, severity, and early progression in multiple sclerosis
BACKGROUND: Iron involvement/imbalance is strongly suspected in multiple sclerosis (MS) etiopathogenesis, but its role is quite debated. Iron deposits encircle the veins in brain MS lesions, increasing local metal concentrations in brain parenchyma as documented by magnetic resonance imaging and his...
Autores principales: | Gemmati, Donato, Zeri, Giulia, Orioli, Elisa, De Gaetano, Francesca E, Salvi, Fabrizio, Bartolomei, Ilaria, D’Alfonso, Sandra, Dall’Osso, Claudia, Leone, Maurizio A, Singh, Ajay V, Asselta, Rosanna, Zamboni, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490944/ https://www.ncbi.nlm.nih.gov/pubmed/22883388 http://dx.doi.org/10.1186/1471-2350-13-70 |
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