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Secreted Aspartic Protease Cleavage of Candida albicans Msb2 Activates Cek1 MAPK Signaling Affecting Biofilm Formation and Oropharyngeal Candidiasis

Perception of external stimuli and generation of an appropriate response are crucial for host colonization by pathogens. In pathogenic fungi, mitogen activated protein kinase (MAPK) pathways regulate dimorphism, biofilm/mat formation, and virulence. Signaling mucins, characterized by a heavily glyco...

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Detalles Bibliográficos
Autores principales: Puri, Sumant, Kumar, Rohitashw, Chadha, Sonia, Tati, Swetha, Conti, Heather R., Hube, Bernhard, Cullen, Paul J., Edgerton, Mira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491010/
https://www.ncbi.nlm.nih.gov/pubmed/23139737
http://dx.doi.org/10.1371/journal.pone.0046020