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Adaptive Evolution and the Birth of CTCF Binding Sites in the Drosophila Genome
Changes in the physical interaction between cis-regulatory DNA sequences and proteins drive the evolution of gene expression. However, it has proven difficult to accurately quantify evolutionary rates of such binding change or to estimate the relative effects of selection and drift in shaping the bi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491045/ https://www.ncbi.nlm.nih.gov/pubmed/23139640 http://dx.doi.org/10.1371/journal.pbio.1001420 |