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Adaptive Evolution and the Birth of CTCF Binding Sites in the Drosophila Genome

Changes in the physical interaction between cis-regulatory DNA sequences and proteins drive the evolution of gene expression. However, it has proven difficult to accurately quantify evolutionary rates of such binding change or to estimate the relative effects of selection and drift in shaping the bi...

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Detalles Bibliográficos
Autores principales: Ni, Xiaochun, Zhang, Yong E., Nègre, Nicolas, Chen, Sidi, Long, Manyuan, White, Kevin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491045/
https://www.ncbi.nlm.nih.gov/pubmed/23139640
http://dx.doi.org/10.1371/journal.pbio.1001420