Comparison on Virulence and Immunogenicity of Two Recombinant Vaccinia Vaccines, Tian Tan and Guang9 Strains, Expressing the HIV-1 Envelope Gene

BACKGROUND: The vaccinia virus Guang9 strain (VG9), derived from the vaccinia virus Tian Tan strain (VTT) has been found to be less virulent than VTT. METHODOLOGY/PRINCIPAL FINDINGS: To investigate whether VG9 could be a potential replicating virus vector, the TK genes in VG9 and VTT were replaced w...

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Detalles Bibliográficos
Autores principales: Zhu, Rong, Huang, Weijin, Wang, Wenbo, Liu, Qiang, Nie, Jianhui, Meng, Shufang, Yu, Yongxin, Wang, Youchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491055/
https://www.ncbi.nlm.nih.gov/pubmed/23139778
http://dx.doi.org/10.1371/journal.pone.0048343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491055/
https://www.ncbi.nlm.nih.gov/pubmed/23139778
http://dx.doi.org/10.1371/journal.pone.0048343

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