Cargando…

Comparison on Virulence and Immunogenicity of Two Recombinant Vaccinia Vaccines, Tian Tan and Guang9 Strains, Expressing the HIV-1 Envelope Gene

BACKGROUND: The vaccinia virus Guang9 strain (VG9), derived from the vaccinia virus Tian Tan strain (VTT) has been found to be less virulent than VTT. METHODOLOGY/PRINCIPAL FINDINGS: To investigate whether VG9 could be a potential replicating virus vector, the TK genes in VG9 and VTT were replaced w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Rong, Huang, Weijin, Wang, Wenbo, Liu, Qiang, Nie, Jianhui, Meng, Shufang, Yu, Yongxin, Wang, Youchun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491055/ https://www.ncbi.nlm.nih.gov/pubmed/23139778 http://dx.doi.org/10.1371/journal.pone.0048343

Ejemplares similares

Deletion of C7L and K1L Genes Leads to Significantly Decreased Virulence of Recombinant Vaccinia Virus TianTan
por: Liu, Zheng, et al.
Publicado: (2013)

The attenuation of vaccinia Tian Tan strain by the removal of the viral M1L-K2L genes
por: Zhu, Weijun, et al.
Publicado: (2007)

Oncolytic efficacy of thymidine kinase-deleted vaccinia virus strain Guang9
por: Deng, Lili, et al.
Publicado: (2017)

Attenuation of Vaccinia Tian Tan Strain by Removal of Viral TC7L-TK2L and TA35R Genes
por: Kan, Shifu, et al.
Publicado: (2012)

Evaluation of Tumor Specificity and Immunity of Thymidine Kinase-Deleted Vaccinia Virus Guang9 Strain
por: Ding, Yuedi, et al.
Publicado: (2020)

A Novel High-Throughput Vaccinia Virus Neutralization Assay and Preexisting Immunity in Populations from Different Geographic Regions in China
por: Liu, Qiang, et al.
Publicado: (2012)

Non-replicating Vaccinia Virus TianTan Strain (NTV) Translation Arrest of Viral Late Protein Synthesis Associated With Anti-viral Host Factor SAMD9
por: Zhao, Ying, et al.
Publicado: (2020)

Bioluminescence imaging of a tumor-selective, thymidine kinase-defective vaccinia virus Guang9 strain after intratumoral or intraperitoneal administration in mice
por: Ding, Yuedi, et al.
Publicado: (2017)

Dr. Tian Xu
por: Ni, Thomas, et al.
Publicado: (2007)

A systematic study of the N-glycosylation sites of HIV-1 envelope protein on infectivity and antibody-mediated neutralization
por: Wang, Wenbo, et al.
Publicado: (2013)

Peritonitis secondary to hemorrhagic fever with renal syndrome: a case report in GuangZhou China
por: Huang, Na, et al.
Publicado: (2020)

Development of a Triple-Color Pseudovirion-Based Assay to Detect Neutralizing Antibodies against Human Papillomavirus
por: Nie, Jianhui, et al.
Publicado: (2016)

HIV-1 pseudoviruses constructed in China regulatory laboratory
por: Nie, Jianhui, et al.
Publicado: (2019)

Comparison of Two High-Throughput Assays for Quantification of Adenovirus Type 5 Neutralizing Antibodies in a Population of Donors in China
por: Liu, Qiang, et al.
Publicado: (2012)

Guang Zeng, China CDC’s Former Chief Expert of Epidemiology
por: Hao, Peter, et al.
Publicado: (2020)

Tri-Co Robots for the future: an interview with Guang-Zhong Yang
por: Li, Tiefeng
Publicado: (2022)

Effect of the Route of Administration of the Vaccinia Virus Strain LIVP to Mice on Its Virulence and Immunogenicity
por: Shchelkunov, Sergei N., et al.
Publicado: (2020)

Enhancing the Immunogenicity of Vaccinia Virus
por: Shchelkunov, Sergei N., et al.
Publicado: (2022)

Comparison of the genotypic and phenotypic properties of HIV-1 standard subtype B and subtype B/B′ env molecular clones derived from infections in China
por: Xie, Hui, et al.
Publicado: (2018)

Genes that Control Vaccinia Virus Immunogenicity
por: Shchelkunov, S. N., et al.
Publicado: (2020)

Liver Transcriptome Response to Heat Stress in Beijing You Chickens and Guang Ming Broilers
por: Barreto Sánchez, Astrid Lissette, et al.
Publicado: (2022)

Single-base editing in IGF2 improves meat production and intramuscular fat deposition in Liang Guang Small Spotted pigs
por: Duo, Tianqi, et al.
Publicado: (2023)

Macrofungal Survey of the Tian Shan Mountains, Kyrgyzstan
por: Cho, Sung Eun, et al.
Publicado: (2019)

Ye Tian: Surveilling stress to live longer
por: Morgado-Palacin, Lucia
Publicado: (2021)

Cross-reactivity of eight SARS-CoV-2 variants rationally predicts immunogenicity clustering in sarbecoviruses
por: Li, Qianqian, et al.
Publicado: (2022)

Antigenic variations of recent street rabies virus
por: Wang, Wenbo, et al.
Publicado: (2019)

Hepatitis E Virus Produced from Cell Culture Has a Lipid Envelope
por: Qi, Ying, et al.
Publicado: (2015)

Recombinant Vaccinia Viruses Coding Transgenes of Apoptosis-Inducing Proteins Enhance Apoptosis But Not Immunogenicity of Infected Tumor Cells
por: Koval, Olga, et al.
Publicado: (2017)

Nipah pseudovirus system enables evaluation of vaccines in vitro and in vivo using non-BSL-4 facilities
por: Nie, Jianhui, et al.
Publicado: (2019)

Geometric analysis: in honor of Gang Tian's 60th birthday
por: Chen, Jingyi, et al.
Publicado: (2020)

Investigation on peculiar SNR variation at TianMa radio telescope
por: He, Qingbao
Publicado: (2019)

Monkeypox virus quadrivalent mRNA vaccine induces immune response and protects against vaccinia virus
por: Sang, Ye, et al.
Publicado: (2023)

Systemically administered DNA and fowlpox recombinants expressing four vaccinia virus genes although immunogenic do not protect mice against the highly pathogenic IHD-J vaccinia strain
por: Bissa, Massimiliano, et al.
Publicado: (2013)

Bioluminescent imaging of vaccinia virus infection in immunocompetent and immunodeficient rats as a model for human smallpox
por: Liu, Qiang, et al.
Publicado: (2015)

Primary structure of the membrane and nucleocapsid protein genes of feline infectious peritonitis virus and immunogenicity of recombinant vaccinia viruses in kittens
por: Vennema, Harry, et al.
Publicado: (1991)

Effect of the ati Gene Deletion on the Pathogenicity and Immunogenicity of the Vaccinia Virus
por: Yakubitskiy, S. N., et al.
Publicado: (2023)

Anti-inflammatory activities of Guang-Pheretima extract in lipopolysaccharide-stimulated RAW 264.7 murine macrophages
por: Huang, Chuanqi, et al.
Publicado: (2018)

Chromatographic Fingerprint and Quantitative Analysis of Commercial Pheretima aspergillum (Guang Dilong) and Its Adulterants by UPLC-DAD
por: Sun, Jie, et al.
Publicado: (2019)

Exploring the Molecular Mechanism of Qing Guang An Granule in Treating Glaucoma Using Network Pharmacology and Molecular Docking
por: Ou, Chen, et al.
Publicado: (2020)

The Antigenicity of Epidemic SARS-CoV-2 Variants in the United Kingdom
por: Wu, Jiajing, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_prn78dcbpblsv1km3n68pa6hdh