Homocysteine Induces Apoptosis of Rat Hippocampal Neurons by Inhibiting 14-3-3ε Expression and Activating Calcineurin

A high level of plasma homocysteine (Hcy) increases the risk for neurodegenerative diseases. One such disorder is Alzheimer’s disease, which involves marked neuronal apoptosis of unknown etiology. This study shows that Hcy inhibits expression of 14-3-3ε and activates calcineurin in rat hippocampal n...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Bai, Xue, Chen, Yongxing, Zhao, Yanxin, Liu, Xueyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491063/
https://www.ncbi.nlm.nih.gov/pubmed/23139767
http://dx.doi.org/10.1371/journal.pone.0048247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491063/
https://www.ncbi.nlm.nih.gov/pubmed/23139767
http://dx.doi.org/10.1371/journal.pone.0048247

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