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Autophagy in proximal tubules protects against acute kidney injury

Autophagy is induced in renal tubular cells during acute kidney injury, however, whether this is protective or injurious remains controversial. We address this question by pharmacologic and genetic blockade of autophagy using mouse models of cisplatin- and ischemia-reperfusion induced acute kidney i...

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Detalles Bibliográficos
Autores principales: Jiang, Man, Wei, Qing-qing, Dong, Guie, Komatsu, Masaaki, Su, Yunchao, Dong, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491167/
https://www.ncbi.nlm.nih.gov/pubmed/22854643
http://dx.doi.org/10.1038/ki.2012.261