Bisphosphonate-induced gastrointestinal mucosal injury is mediated by mitochondrial superoxide production and lipid peroxidation

Bisphosphonates such as alendronate and risedronate are commonly used for the treatment of postmenopausal osteoporosis. They have the gastrointestinal adverse effects such as erosions and ulcers in stomach and small intestine. However, the detailed biological mechanism remains to be elucidated. Sinc...

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Detalles Bibliográficos
Autores principales: Nagano, Yumiko, Matsui, Hirofumi, Shimokawa, Osamu, Hirayama, Aki, Nakamura, Yukio, Tamura, Masato, Rai, Kanho, Kaneko, Tsuyoshi, Hyodo, Ichinosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491244/
https://www.ncbi.nlm.nih.gov/pubmed/23170047
http://dx.doi.org/10.3164/jcbn.12-41

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491244/
https://www.ncbi.nlm.nih.gov/pubmed/23170047
http://dx.doi.org/10.3164/jcbn.12-41

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