Genome-wide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase

BACKGROUND: Methylation of cytosine in DNA (5mC) is an important epigenetic mark that is involved in the regulation of genome function. During early embryonic development in mammals, the methylation landscape is dynamically reprogrammed in part through active demethylation. Recent advances have iden...

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Detalles Bibliográficos
Autores principales: Raiber, Eun-Ang, Beraldi, Dario, Ficz, Gabriella, Burgess, Heather E, Branco, Miguel R, Murat, Pierre, Oxley, David, Booth, Michael J, Reik, Wolf, Balasubramanian, Shankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491369/
https://www.ncbi.nlm.nih.gov/pubmed/22902005
http://dx.doi.org/10.1186/gb-2012-13-8-r69

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491369/
https://www.ncbi.nlm.nih.gov/pubmed/22902005
http://dx.doi.org/10.1186/gb-2012-13-8-r69

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