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A gene expression profile of stem cell pluripotentiality and differentiation is conserved across diverse solid and hematopoietic cancers

BACKGROUND: Understanding the fundamental mechanisms of tumorigenesis remains one of the most pressing problems in modern biology. To this end, stem-like cells with tumor-initiating potential have become a central focus in cancer research. While the cancer stem cell hypothesis presents a compelling...

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Detalles Bibliográficos
Autores principales: Palmer, Nathan P, Schmid, Patrick R, Berger, Bonnie, Kohane, Isaac S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491371/
https://www.ncbi.nlm.nih.gov/pubmed/22909066
http://dx.doi.org/10.1186/gb-2012-13-8-r71