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A gene expression profile of stem cell pluripotentiality and differentiation is conserved across diverse solid and hematopoietic cancers
BACKGROUND: Understanding the fundamental mechanisms of tumorigenesis remains one of the most pressing problems in modern biology. To this end, stem-like cells with tumor-initiating potential have become a central focus in cancer research. While the cancer stem cell hypothesis presents a compelling...
Autores principales: | Palmer, Nathan P, Schmid, Patrick R, Berger, Bonnie, Kohane, Isaac S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491371/ https://www.ncbi.nlm.nih.gov/pubmed/22909066 http://dx.doi.org/10.1186/gb-2012-13-8-r71 |
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