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Bis-SNP: Combined DNA methylation and SNP calling for Bisulfite-seq data

Bisulfite treatment of DNA followed by high-throughput sequencing (Bisulfite-seq) is an important method for studying DNA methylation and epigenetic gene regulation, yet current software tools do not adequately address single nucleotide polymorphisms (SNPs). Identifying SNPs is important for accurat...

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Detalles Bibliográficos
Autores principales: Liu, Yaping, Siegmund, Kimberly D, Laird, Peter W, Berman, Benjamin P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491382/
https://www.ncbi.nlm.nih.gov/pubmed/22784381
http://dx.doi.org/10.1186/gb-2012-13-7-r61