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Developmental features of DNA methylation during activation of the embryonic zebrafish genome

BACKGROUND: Zygotic genome activation (ZGA) occurs at the mid-blastula transition (MBT) in zebrafish and is a period of extensive chromatin remodeling. Genome-scale gametic demethylation and remethylation occurs after fertilization, during blastula stages, but how ZGA relates to promoter DNA methyla...

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Detalles Bibliográficos
Autores principales: Andersen, Ingrid S, Reiner, Andrew H, Aanes, Håvard, Aleström, Peter, Collas, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491385/
https://www.ncbi.nlm.nih.gov/pubmed/22830626
http://dx.doi.org/10.1186/gb-2012-13-7-r65