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DNA methylation studies using twins: what are they telling us?
Recent studies have identified both heritable DNA methylation effects and differential methylation in disease-discordant identical twins. Larger sample sizes, replication, genetic-epigenetic analyses and longitudinal assays are now needed to establish the role of epigenetic variants in disease.
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491399/ https://www.ncbi.nlm.nih.gov/pubmed/23078798 http://dx.doi.org/10.1186/gb-2012-13-10-172 |
| _version_ | 1782248988018212864 |
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| author | Bell, Jordana T Spector, Tim D |
| author_facet | Bell, Jordana T Spector, Tim D |
| author_sort | Bell, Jordana T |
| collection | PubMed |
| description | Recent studies have identified both heritable DNA methylation effects and differential methylation in disease-discordant identical twins. Larger sample sizes, replication, genetic-epigenetic analyses and longitudinal assays are now needed to establish the role of epigenetic variants in disease. |
| format | Online Article Text |
| id | pubmed-3491399 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2012 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-34913992012-11-08 DNA methylation studies using twins: what are they telling us? Bell, Jordana T Spector, Tim D Genome Biol Opinion Recent studies have identified both heritable DNA methylation effects and differential methylation in disease-discordant identical twins. Larger sample sizes, replication, genetic-epigenetic analyses and longitudinal assays are now needed to establish the role of epigenetic variants in disease. BioMed Central 2012 2012-10-18 /pmc/articles/PMC3491399/ /pubmed/23078798 http://dx.doi.org/10.1186/gb-2012-13-10-172 Text en Copyright ©2012 BioMed Central Ltd |
| spellingShingle | Opinion Bell, Jordana T Spector, Tim D DNA methylation studies using twins: what are they telling us? |
| title | DNA methylation studies using twins: what are they telling us? |
| title_full | DNA methylation studies using twins: what are they telling us? |
| title_fullStr | DNA methylation studies using twins: what are they telling us? |
| title_full_unstemmed | DNA methylation studies using twins: what are they telling us? |
| title_short | DNA methylation studies using twins: what are they telling us? |
| title_sort | dna methylation studies using twins: what are they telling us? |
| topic | Opinion |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491399/ https://www.ncbi.nlm.nih.gov/pubmed/23078798 http://dx.doi.org/10.1186/gb-2012-13-10-172 |
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