DNA methylation studies using twins: what are they telling us?

Recent studies have identified both heritable DNA methylation effects and differential methylation in disease-discordant identical twins. Larger sample sizes, replication, genetic-epigenetic analyses and longitudinal assays are now needed to establish the role of epigenetic variants in disease.

Detalles Bibliográficos
Autores principales: Bell, Jordana T, Spector, Tim D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Opinion
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491399/
https://www.ncbi.nlm.nih.gov/pubmed/23078798
http://dx.doi.org/10.1186/gb-2012-13-10-172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491399/
https://www.ncbi.nlm.nih.gov/pubmed/23078798
http://dx.doi.org/10.1186/gb-2012-13-10-172

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