Cargando…

methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles

DNA methylation is a chemical modification of cytosine bases that is pivotal for gene regulation, cellular specification and cancer development. Here, we describe an R package, methylKit, that rapidly analyzes genome-wide cytosine epigenetic profiles from high-throughput methylation and hydroxymethy...

Descripción completa

Detalles Bibliográficos
Autores principales: Akalin, Altuna, Kormaksson, Matthias, Li, Sheng, Garrett-Bakelman, Francine E, Figueroa, Maria E, Melnick, Ari, Mason, Christopher E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491415/
https://www.ncbi.nlm.nih.gov/pubmed/23034086
http://dx.doi.org/10.1186/gb-2012-13-10-r87