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methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles
DNA methylation is a chemical modification of cytosine bases that is pivotal for gene regulation, cellular specification and cancer development. Here, we describe an R package, methylKit, that rapidly analyzes genome-wide cytosine epigenetic profiles from high-throughput methylation and hydroxymethy...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491415/ https://www.ncbi.nlm.nih.gov/pubmed/23034086 http://dx.doi.org/10.1186/gb-2012-13-10-r87 |