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Analysis of Notch and TGF-β Signaling Expression in Different Stages of Disease Progression During Hepatitis B Virus Infection

OBJECTIVES: CD4+ regulatory T cells (Tregs) seem to have a key role in persistence of hepatitis B virus (HBV) infection. Notch and transforming growth factor (TGF-β) signaling independently help in the differentiation and regulation of CD4+T cells, including T-helper (T(H)) 1, T(H)2, and Tregs. Whet...

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Detalles Bibliográficos
Autores principales: Trehanpati, Nirupama, Shrivastav, Shikha, Shivakumar, Bhavana, Khosla, Ritu, Bhardwaj, Suvercha, Chaturvedi, Jaya, Sukriti, Kumar, Binayak, Bose, Sujoy, Mani Tripathi, Dinesh, Das, Trinath, Sakhuja, Puja, Rastogi, Archana, Bhihari, Chagan, Singh, Shivender, Gupta, Subhash, Kottilil, Shyam, Sarin, Shiv Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491533/
https://www.ncbi.nlm.nih.gov/pubmed/23238065
http://dx.doi.org/10.1038/ctg.2012.17