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Systematic review: cardiovascular safety profile of 5-HT(4) agonists developed for gastrointestinal disorders

BACKGROUND: The nonselective 5-HT(4) receptor agonists, cisapride and tegaserod have been associated with cardiovascular adverse events (AEs). AIM: To perform a systematic review of the safety profile, particularly cardiovascular, of 5-HT(4) agonists developed for gastrointestinal disorders, and a n...

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Detalles Bibliográficos
Autores principales: Tack, J, Camilleri, M, Chang, L, Chey, W D, Galligan, J J, Lacy, B E, Müller-Lissner, S, Quigley, E M M, Schuurkes, J, Maeyer, J H, Stanghellini, V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491670/
https://www.ncbi.nlm.nih.gov/pubmed/22356640
http://dx.doi.org/10.1111/j.1365-2036.2012.05011.x