Sphingosine regulates the NLRP3-inflammasome and IL-1β release from macrophages

Interleukin-1β (IL-1β) is a pro-inflammatory cytokine that regulates inflammatory responses to injury and infection. IL-1β secretion requires the protease caspase-1, which is activated following recruitment to inflammasomes. Endogenous danger-associated molecular patterns (DAMPs) released from necro...

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Detalles Bibliográficos
Autores principales: Luheshi, Nadia M, Giles, James A, Lopez-Castejon, Gloria, Brough, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2012
Materias:
Innate Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491674/
https://www.ncbi.nlm.nih.gov/pubmed/22105559
http://dx.doi.org/10.1002/eji.201142079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491674/
https://www.ncbi.nlm.nih.gov/pubmed/22105559
http://dx.doi.org/10.1002/eji.201142079

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