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Preventing acute gut wall damage in infectious diarrhoeas with glycosylated dendrimers

Intestinal pathogens use the host's excessive inflammatory cytokine response, designed to eliminate dangerous bacteria, to disrupt epithelial gut wall integrity and promote their tissue invasion. We sought to develop a non-antibiotic-based approach to prevent this injury. Molecular docking stud...

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Detalles Bibliográficos
Autores principales: Teo, Ian, Toms, Steve M, Marteyn, Benoit, Barata, Teresa S, Simpson, Peter, Johnston, Karen A, Schnupf, Pamela, Puhar, Andrea, Bell, Tracey, Tang, Chris, Zloh, Mire, Matthews, Steve, Rendle, Phillip M, Sansonetti, Philippe J, Shaunak, Sunil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491821/
https://www.ncbi.nlm.nih.gov/pubmed/22887873
http://dx.doi.org/10.1002/emmm.201201290