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Preventing acute gut wall damage in infectious diarrhoeas with glycosylated dendrimers
Intestinal pathogens use the host's excessive inflammatory cytokine response, designed to eliminate dangerous bacteria, to disrupt epithelial gut wall integrity and promote their tissue invasion. We sought to develop a non-antibiotic-based approach to prevent this injury. Molecular docking stud...
Autores principales: | Teo, Ian, Toms, Steve M, Marteyn, Benoit, Barata, Teresa S, Simpson, Peter, Johnston, Karen A, Schnupf, Pamela, Puhar, Andrea, Bell, Tracey, Tang, Chris, Zloh, Mire, Matthews, Steve, Rendle, Phillip M, Sansonetti, Philippe J, Shaunak, Sunil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491821/ https://www.ncbi.nlm.nih.gov/pubmed/22887873 http://dx.doi.org/10.1002/emmm.201201290 |
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