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Molecular network analysis of human microRNA targetome: from cancers to Alzheimer’s disease

MicroRNAs (miRNAs), a class of endogenous small noncoding RNAs, mediate posttranscriptional regulation of protein-coding genes by binding chiefly to the 3’ untranslated region of target mRNAs, leading to translational inhibition, mRNA destabilization or degradation. A single miRNA concurrently downr...

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Detalles Bibliográficos
Autor principal: Satoh, Jun-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492042/
https://www.ncbi.nlm.nih.gov/pubmed/23034144
http://dx.doi.org/10.1186/1756-0381-5-17