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Lipoteichoic acid induces surfactant protein-A biosynthesis in human alveolar type II epithelial cells through activating the MEK1/2-ERK1/2-NF-κB pathway

BACKGROUND: Lipoteichoic acid (LTA), a gram-positive bacterial outer membrane component, can cause septic shock. Our previous studies showed that the gram-negative endotoxin, lipopolysaccharide (LPS), could induce surfactant protein-A (SP-A) production in human alveolar epithelial (A549) cells. OBJE...

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Detalles Bibliográficos
Autores principales: Liu, Feng-Lin, Chuang, Chi-Yuan, Tai, Yu-Ting, Tang, Hsiu-Lien, Chen, Tyng-Guey, Chen, Ta-Liang, Chen, Ruei-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492077/
https://www.ncbi.nlm.nih.gov/pubmed/23031213
http://dx.doi.org/10.1186/1465-9921-13-88