Neuroprotective effect of an angiotensin receptor type 2 agonist following cerebral ischemia in vitro and in vivo

BACKGROUND: Intracerebral administration of the angiotensin II type 2 receptor (AT(2)R) agonist, CGP42112, is neuroprotective in a rat model of ischemic stroke. To explore further its possible cellular target(s) and therapeutic utility, we firstly examined whether CGP42112 may exert direct protectiv...

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Detalles Bibliográficos
Autores principales: Lee, Seyoung, Brait, Vanessa H, Arumugam, Thiruma V, Evans, Megan A, Kim, Hyun Ah, Widdop, Robert E, Drummond, Grant R, Sobey, Christopher G, Jones, Emma S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492080/
https://www.ncbi.nlm.nih.gov/pubmed/22920387
http://dx.doi.org/10.1186/2040-7378-4-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492080/
https://www.ncbi.nlm.nih.gov/pubmed/22920387
http://dx.doi.org/10.1186/2040-7378-4-16

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