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A20 Controls Macrophage to Elicit Potent Cytotoxic CD4(+) T Cell Response

Emerging evidence indicates that CD4(+) T cells possess cytotoxic potential for tumor eradication and perforin/granzyme-mediated cytotoxicity functions as one of the important mechanisms for CD4(+) T cell-triggered cell killing. However, the critical issue is how the cytotoxic CD4(+) T cells are dev...

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Detalles Bibliográficos
Autores principales: Wang, Lifeng, Hong, Bangxing, Jiang, Xiaoxia, Jones, Lindsey, Chen, Si-Yi, Huang, Xue F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492139/
https://www.ncbi.nlm.nih.gov/pubmed/23145026
http://dx.doi.org/10.1371/journal.pone.0048930