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Phosphorylation of transglutaminase 2 (TG2) at serine-216 has a role in TG2 mediated activation of nuclear factor-kappa B and in the downregulation of PTEN

BACKGROUND: Transglutaminase 2 (TG2) and its phosphorylation have been consistently found to be upregulated in a number of cancer cell types. At the molecular level, TG2 has been associated with the activation of nuclear factor-kappa B (NF-κB), protein kinase B (PKB/Akt) and in the downregulation of...

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Detalles Bibliográficos
Autores principales: Wang, Yi, Ande, Sudharsana R, Mishra, Suresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492171/
https://www.ncbi.nlm.nih.gov/pubmed/22759359
http://dx.doi.org/10.1186/1471-2407-12-277