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Apoptosis-Related Gene Expression Profiles of Mouse ESCs and maGSCs: Role of Fgf4 and Mnda in Pluripotent Cell Responses to Genotoxicity

Stem cells in the developing embryo proliferate and differentiate while maintaining genomic integrity, failure of which may lead to accumulation of mutations and subsequent damage to the embryo. Embryonic stem cells (ESCs), the in vitro counterpart of embryo stem cells are highly sensitive to genoto...

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Detalles Bibliográficos
Autores principales: Khromov, Tatjana, Dressel, Ralf, Siamishi, Iliana, Nolte, Jessica, Opitz, Lennart, Engel, Wolfgang, Pantakani, D. V. Krishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492253/
https://www.ncbi.nlm.nih.gov/pubmed/23145002
http://dx.doi.org/10.1371/journal.pone.0048869