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Apoptosis-Related Gene Expression Profiles of Mouse ESCs and maGSCs: Role of Fgf4 and Mnda in Pluripotent Cell Responses to Genotoxicity
Stem cells in the developing embryo proliferate and differentiate while maintaining genomic integrity, failure of which may lead to accumulation of mutations and subsequent damage to the embryo. Embryonic stem cells (ESCs), the in vitro counterpart of embryo stem cells are highly sensitive to genoto...
Autores principales: | Khromov, Tatjana, Dressel, Ralf, Siamishi, Iliana, Nolte, Jessica, Opitz, Lennart, Engel, Wolfgang, Pantakani, D. V. Krishna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492253/ https://www.ncbi.nlm.nih.gov/pubmed/23145002 http://dx.doi.org/10.1371/journal.pone.0048869 |
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