Enhanced Antitumor Efficacy and Reduced Systemic Toxicity of Sulfatide-Containing Nanoliposomal Doxorubicin in a Xenograft Model of Colorectal Cancer

Sulfatide is a glycosphingolipid known to interact with several extracellular matrix proteins, such as tenascin-C which is overexpressed in many types of cancer including that of the colon. In view of the limited success of chemotherapy in colorectal cancer and high toxicity of doxorubicin (DOX), a...

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Detalles Bibliográficos
Autores principales: Lin, Jia, Yu, Yan, Shigdar, Sarah, Fang, Ding Zhi, Du, Jun Rong, Wei, Ming Q., Danks, Andrew, Liu, Ke, Duan, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492268/
https://www.ncbi.nlm.nih.gov/pubmed/23145140
http://dx.doi.org/10.1371/journal.pone.0049277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492268/
https://www.ncbi.nlm.nih.gov/pubmed/23145140
http://dx.doi.org/10.1371/journal.pone.0049277

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